SCHEMBL9022367

SCHEMBL9022367

O=C(c1ccc(C(F)(F)F)cc1)C(Br)CCBr

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.64
PTPN1 P18031 2/20 0.54
CES2 O00748 2/20 0.51
CES1 P23141 2/20 0.51
SLC6A4 P31645 1/20 0.46
SRD5A2 P31213 2/20 0.43
PDPK1 O15530 1/20 0.42
MMP1 P03956 1/20 0.41
LMNA P02545 1/20 0.40
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD11B1 P28845 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC8 Q9BY41 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4940165 0.85 GSK3B (0.62) GSK3BPTPN1CES2CES1SLC6A4
SCHEMBL5052384 0.80 GSK3B (0.64) GSK3BPTPN1CES2CES1SLC6A4
SCHEMBL6784646 0.78 GSK3B (1.00) GSK3BPTPN1CES2CES1SLC6A4
SCHEMBL5214256 0.77 GSK3B (0.47) GSK3BPTPN1CES2CES1LMNA
SCHEMBL786834 0.75 GSK3B (0.72) GSK3BPTPN1CES2CES1SLC6A4
SCHEMBL8561475 0.74 MTOR (0.47) MEN1KMT2AHDAC1HDAC8
SCHEMBL8561477 0.74 MTOR (0.47) MEN1KMT2AHDAC1HDAC8
SCHEMBL31557731 0.73 PTPN1 (0.75) GSK3BPTPN1CES2CES1SRD5A2
SCHEMBL10847368 0.72 CES2 (0.69) GSK3BPTPN1CES2CES1SLC6A4
SCHEMBL8534398 0.71 GSK3B (0.66) GSK3BPTPN1CES2CES1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699669-A1 TRIAZOLE DERIVATIVE OR SALT THEREOF, AND FUNGICIDE CONTAINING THE SAME SS PHARMACEUTICAL CO., LTD. (JP) 1996-03-06 EP disclosed