Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 14/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glenvastatin SCHEMBL29557142 | 0.96 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL1040744 | 0.96 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL9872411 | 0.96 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9022892 | 0.96 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL1040745 | 0.96 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL49508 | 0.96 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL1660022 | 0.96 | HMGCR (1.00) | HMGCR | |
| Glenvastatin SCHEMBL10024037 | 0.96 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9022974 | 0.94 | HMGCR (0.88) | HMGCR | |
| SCHEMBL10425480 | 0.94 | HMGCR (0.88) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319847-B1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 3-DESMETHYLMEVALONIC ACID DERIVATIVES AND INTERMEDIATE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4977279-A | Anticholesterol agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-12-11 | — | — | US | disclosed |
| US-4970313-A | Optically active 3-demethylmevalonic acid derivatives, and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | disclosed |
| EP-0319847-A2 | Method for the preparation of optically active 3-desmethylmevalonic acid derivatives and intermediate compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-14 | — | — | EP | disclosed |