Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.42 |
| ▸ | BCHE | P06276 | 12/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811897 | 0.77 | ACHE (0.42) | ACHEBCHE | |
| SCHEMBL9025548 | 0.76 | ACHE (0.41) | ACHEBCHE | |
| 1-Ethylquinolonium SCHEMBL309459 | 0.68 | ACHE (0.63) | ACHEBCHEKDM4EMEN1RGS12 | |
| SCHEMBL12589454 | 0.68 | BCHE (0.61) | ACHEBCHEKDM4EMEN1RGS12 | |
| SCHEMBL9478372 | 0.68 | ACHE (0.38) | ACHEBCHE | |
| 1-Ethylquinolonium SCHEMBL186988 | 0.67 | KDM4E (0.62) | ACHEBCHEKDM4EMEN1RGS12 | |
| 1-Ethylquinolonium SCHEMBL10655763 | 0.67 | ACHE (0.64) | ACHEBCHE | |
| 1-Ethylquinolonium SCHEMBL30920082 | 0.67 | KDM4E (0.62) | ACHEBCHEKDM4EMEN1RGS12 | |
| 1-Ethylquinolonium SCHEMBL18804795 | 0.67 | ACHE (0.61) | ACHEBCHEKDM4EMEN1RGS12 | |
| 1-Ethylquinolonium SCHEMBL9135771 | 0.67 | ACHE (0.62) | ACHEBCHEKDM4EMEN1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390099-B1 | Polar cephalosporin derivatives and process for their preparation | HOECHST AG (DE) | 1996-06-26 | — | — | EP | disclosed |
| EP-0390099-A2 | Polar cephalosporin derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-03 | — | — | EP | disclosed |