SCHEMBL9023065

SCHEMBL9023065

CN1C(=O)C=C[C@]2(C)[C@H]3CC[C@]4(C)[C@@H](OC(=O)NC(C)(C)c5cccs5)CC[C@H]4[C@@H]3CC[C@@H]12

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 8/20 0.53
SRD5A2 P31213 1/20 0.48
KCNH2 Q12809 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9022687 0.87 AR (0.56) ARSRD5A2KCNH2
SCHEMBL9022008 0.87 AR (0.62) ARSRD5A2KCNH2
SCHEMBL9022012 0.87 AR (0.62) ARSRD5A2KCNH2
SCHEMBL9022588 0.85 SRD5A2 (0.49) SRD5A2
SCHEMBL9021886 0.84 SRD5A1 (0.57) SRD5A2
SCHEMBL9022594 0.84 AR (0.54) ARSRD5A2KCNH2
SCHEMBL7610600 0.80 AR (0.71) ARSRD5A2KCNH2
SCHEMBL7610596 0.80 AR (0.71) ARSRD5A2KCNH2
SCHEMBL8823341 0.79 AR (0.70) ARSRD5A2KCNH2
SCHEMBL9023095 0.79 AR (0.57) ARSRD5A2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0484094-B1 Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO CO (JP) 1996-06-26 EP claimed