Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022423 | 0.74 | SLC6A4 (0.38) | HRH3PDE4B | |
| SCHEMBL31202927 | 0.72 | IKBKB (0.47) | RAB9AHRH3MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL9013901 | 0.71 | IKBKB (0.46) | RAB9AHRH3MEN1KMT2ATDP1 | |
| SCHEMBL15061997 | 0.69 | EPHX2 (0.59) | RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL31202998 | 0.69 | ALDH1A1 (0.49) | RAB9AMEN1KMT2ATDP1PDE4B | |
| SCHEMBL9014162 | 0.69 | ALDH1A1 (0.49) | RAB9AMEN1KMT2ATDP1PDE4B | |
| SCHEMBL11345753 | 0.68 | ALDH1A1 (0.42) | TDP1MAPT | |
| SCHEMBL9013850 | 0.68 | NAMPT (0.49) | HRH3MAPT | |
| SCHEMBL9022461 | 0.67 | TOP2A (0.35) | PDE4B | |
| SCHEMBL12311796 | 0.67 | POLB (0.52) | RAB9AHRH3MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |