Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 15/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006313 | 1.00 | TBXAS1 (0.47) | TBXAS1TBXA2RKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9024135 | 0.95 | TBXAS1 (0.48) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9006194 | 0.95 | TBXAS1 (0.48) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9006132 | 0.95 | TBXAS1 (0.46) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9024389 | 0.95 | TBXAS1 (0.46) | TBXAS1TBXA2RKDM4E | |
| SCHEMBL9024488 | 0.91 | TBXAS1 (0.55) | TBXAS1TBXA2R | |
| SCHEMBL9006073 | 0.91 | TBXAS1 (0.55) | TBXAS1TBXA2R | |
| SCHEMBL9006086 | 0.89 | TBXAS1 (0.49) | TBXAS1TBXA2R | |
| SCHEMBL9006093 | 0.89 | TBXAS1 (0.49) | TBXAS1TBXA2R | |
| SCHEMBL9006185 | 0.88 | TBXA2R (0.43) | TBXAS1TBXA2RALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5264453-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5130323-A | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0367130-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |