Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530782 | 0.87 | SRD5A2 (0.64) | SRD5A2MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL1013895 | 0.87 | SRD5A2 (0.64) | SRD5A2MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL837602 | 0.83 | L3MBTL1 (0.51) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL16632761 | 0.79 | SRD5A2 (0.55) | SRD5A2MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL7054784 | 0.76 | MAPT (0.56) | SRD5A2MAPTMAPK1TDP1L3MBTL1 | |
| Indole SCHEMBL28308979 | 0.74 | DRD4 (0.56) | SRD5A2MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL3207672 | 0.72 | SRD5A2 (0.56) | SRD5A2MAPTMAPK1L3MBTL1HTR1A | |
| SCHEMBL29415608 | 0.72 | DRD4 (0.63) | SRD5A2MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL746079 | 0.72 | DRD4 (0.63) | SRD5A2MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL5768529 | 0.71 | SRD5A2 (0.61) | SRD5A2MAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548250-B1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE POULENC RORER INT (US) | 1996-03-27 | — | — | EP | disclosed |