Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023291 | 0.89 | KMT2A (0.44) | KMT2ATOP1KCNH2EPHA2FLT4 | |
| SCHEMBL9023930 | 0.83 | MEN1 (0.46) | KMT2AKCNH2GSK3BKDM4EALDH1A1 | |
| SCHEMBL9023391 | 0.81 | TOP1 (0.42) | KMT2ATOP1KCNH2KDM4EALDH1A1 | |
| SCHEMBL9022786 | 0.81 | KMT2A (0.46) | KMT2ATOP1KCNH2EPHA2FLT4 | |
| SCHEMBL10914315 | 0.77 | TOP1 (0.42) | KMT2ATOP1KCNH2KDM4EALDH1A1 | |
| SCHEMBL10434974 | 0.77 | KMT2A (0.36) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL6214215 | 0.76 | HTT (0.44) | KMT2ATOP1EPHA2FLT4GSK3B | |
| SCHEMBL6213815 | 0.76 | KMT2A (0.35) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9023061 | 0.75 | TOP1 (0.38) | KMT2ATOP1KCNH2KDM4EALDH1A1 | |
| SCHEMBL9023449 | 0.75 | KCNH2 (0.53) | TOP1KCNH2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500835-B1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAE WOONG PHARMA (KR) | 1996-12-27 | — | — | EP | claimed |