Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023291 | 0.92 | KMT2A (0.44) | KMT2ASTAT3MEN1EPHA2FLT4 | |
| SCHEMBL9023293 | 0.88 | KMT2A (0.51) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9663694 | 0.87 | KMT2A (0.47) | KMT2ASTAT3MEN1EPHA2FLT4 | |
| SCHEMBL9023446 | 0.81 | KMT2A (0.37) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9022426 | 0.81 | MEN1 (0.64) | KMT2AMEN1GSK3BALDH1A1KDM4E | |
| SCHEMBL9023391 | 0.79 | TOP1 (0.42) | KMT2ATOP1ALDH1A1KDM4EHPGD | |
| SCHEMBL5868717 | 0.79 | KMT2A (0.60) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL8619695 | 0.79 | KMT2A (0.60) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL10434972 | 0.78 | KMT2A (0.43) | KMT2ASTAT3MEN1EPHA2FLT4 | |
| SCHEMBL8890224 | 0.77 | KMT2A (0.57) | KMT2AEPHA2FLT4GSK3BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500835-B1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAE WOONG PHARMA (KR) | 1996-12-27 | — | — | EP | disclosed |