Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538971 | 0.85 | — | — | |
| SCHEMBL3252979 | 0.82 | FFAR3 (0.41) | FFAR3ALDH1A1TSHRMEN1KMT2A | |
| Acetonitrile SCHEMBL28239628 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9023718 | 0.79 | ALDH1A1 (0.45) | FFAR3ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL20059261 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL28143985 | 0.77 | TET2 (0.45) | FFAR3ALDH1A1TSHR | |
| SCHEMBL6043162 | 0.74 | — | — | |
| SCHEMBL6043172 | 0.74 | — | — | |
| SCHEMBL3305001 | 0.70 | LAP3 (0.34) | — | |
| Bicarbonate SCHEMBL10931175 | 0.70 | TSHR (0.33) | ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725063-A1 | Quinoline derivatives | CIBA-GEIGY AG (CH) | 1996-08-07 | — | — | EP | disclosed |