Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.37 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023894 | 1.00 | CYP4F2 (0.52) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL28307711 | 0.84 | CYP4F2 (0.52) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL28566875 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL8881122 | 0.83 | CYP4F2 (0.76) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL8881119 | 0.83 | CYP4F2 (0.76) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL28307708 | 0.81 | MAPT (0.55) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL28307705 | 0.81 | MAPT (0.55) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL28308489 | 0.81 | MAOB (0.48) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL10891880 | 0.80 | PAM (0.61) | CYP4F2CYP4A11PAMCTDSP1MAOB | |
| SCHEMBL10891882 | 0.80 | PAM (0.61) | CYP4F2CYP4A11PAMCTDSP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699668-A1 | 1-(2-BENZIMIDAZOLYL)-1,5-DIAZACYCLOOCTANE DERIVATIVE | Kissei Pharmaceutical Co., Ltd. (JP) | 1996-03-06 | — | — | EP | disclosed |