Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566875 | 0.86 | CYP4F2 (0.54) | MAPTKMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL30427916 | 0.85 | CYP4F2 (0.65) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL28308489 | 0.83 | MAOB (0.48) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL28307708 | 0.83 | MAPT (0.55) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL10891882 | 0.83 | PAM (0.61) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL10891880 | 0.83 | PAM (0.61) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL28307709 | 0.82 | L3MBTL1 (0.55) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL9023894 | 0.81 | CYP4F2 (0.52) | MAOBCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL9023889 | 0.81 | CYP4F2 (0.52) | MAOBCYP4F2CYP4A11CA12CA1 | |
| SCHEMBL10943888 | 0.81 | PAM (0.50) | KMT2ALMNAMEN1SMN1; SMN2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912418-B | Preparation method of trans-4-phenyl-3-ethyl crotonate compound | 大连理工大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-109912418-A | A kind of preparation method of trans- -4- phenyl -3-butenoic acid ethyl ester compound | 大连理工大学 | 2019-06-21 | — | — | CN | disclosed |