Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292014 | 0.93 | ACHE (0.50) | ACHEEPHX1RECQLALDH1A1HSD17B10 | |
| SCHEMBL9374452 | 0.87 | ACHE (0.55) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL3424560 | 0.83 | ACHE (0.50) | ACHEALDH1A1 | |
| SCHEMBL23891551 | 0.82 | ACHE (0.58) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL461365 | 0.82 | ACHE (0.58) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL12164713 | 0.82 | ACHE (0.50) | ACHEEPHX1 | |
| SCHEMBL606986 | 0.82 | ACHE (0.62) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL4696577 | 0.81 | ACHE (0.62) | ACHEEPHX1 | |
| SCHEMBL8073056 | 0.81 | ACHE (0.49) | ACHEEPHX1 | |
| Hydrochloric Acid SCHEMBL2185194 | 0.81 | ACHE (0.56) | ACHEEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385050-A1 | A process for preparing a substituted oxazole | Schering Corporation (US) | 2011-11-09 | — | — | EP | disclosed |
| US-7507832-B2 | Triazole PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| EP-0721449-A1 | INHIBITORS OF $g(b)-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-17 | — | — | EP | disclosed |
| WO-1995009838-A1 | INHIBITORS OF β-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMACEUTICALS INC. (US) | 1995-04-13 | — | — | WO | disclosed |