Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | MC5R | P33032 | 2/20 | 0.37 |
| ▸ | MC3R | P41968 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024134 | 0.80 | MC4R (0.40) | PRSS1PRSS2PRSS3LMNAMC4R | |
| SCHEMBL9021689 | 0.79 | GRIK1 (0.36) | MAPT | |
| SCHEMBL9021692 | 0.79 | GRIK1 (0.36) | MAPT | |
| SCHEMBL6235454 | 0.77 | PTGS1 (0.37) | — | |
| SCHEMBL29587699 | 0.76 | FAAH (0.49) | ZDHHC2FAAH | |
| SCHEMBL29163485 | 0.76 | FAAH (0.49) | ZDHHC2FAAH | |
| SCHEMBL28822992 | 0.76 | FAAH (0.49) | ZDHHC2FAAH | |
| SCHEMBL29588120 | 0.76 | FAAH (0.49) | ZDHHC2FAAH | |
| SCHEMBL29587784 | 0.75 | FAAH (0.47) | ZDHHC2FAAH | |
| SCHEMBL6754891 | 0.73 | MEN1 (0.51) | LMNAMAPTZDHHC2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720620-A1 | GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS | TERRAPIN TECHNOLOGIES, INC. (US) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008563-A1 | GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS | TERRAPIN TECHNOLOGIES, INC. (US) | 1995-03-30 | — | — | WO | disclosed |