Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021692 | 1.00 | GRIK1 (0.36) | GRIK1GRIK2PTGS1SLC7A11KMT2A | |
| SCHEMBL6235454 | 0.98 | PTGS1 (0.37) | GRIK1GRIK2PTGS1SLC7A11 | |
| SCHEMBL30906927 | 0.81 | FAAH (0.46) | PTGS1KMT2AMAPTPPARGPPARD | |
| SCHEMBL4635625 | 0.80 | PTGS1 (0.50) | PTGS1SLC7A11 | |
| SCHEMBL4635622 | 0.80 | PTGS1 (0.50) | PTGS1SLC7A11 | |
| SCHEMBL30861880 | 0.79 | ALDH1A1 (0.40) | GRIK1GRIK2PTGS1KMT2AMAPT | |
| SCHEMBL9023977 | 0.79 | PRSS1 (0.40) | MAPT | |
| SCHEMBL3806233 | 0.78 | GPR84 (0.44) | GRIK1GRIK2KMT2APPARGPPARD | |
| SCHEMBL7260987 | 0.78 | GPR84 (0.44) | GRIK1GRIK2KMT2APPARGPPARD | |
| SCHEMBL27902175 | 0.78 | GPR84 (0.44) | GRIK1GRIK2KMT2APPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720620-A1 | GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS | TERRAPIN TECHNOLOGIES, INC. (US) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008563-A1 | GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS | TERRAPIN TECHNOLOGIES, INC. (US) | 1995-03-30 | — | — | WO | disclosed |