Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024961 | 0.91 | ALDH1A1 (0.35) | GABRA2GABRB2ALDH1A1 | |
| SCHEMBL649969 | 0.76 | TLR8 (0.39) | TLR8TLR7KDM4ETYMPALDH1A1 | |
| SCHEMBL9025130 | 0.75 | NPSR1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL6416413 | 0.73 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL1256041 | 0.71 | PDE10A (0.31) | KDM4EALDH1A1 | |
| SCHEMBL11324625 | 0.70 | TLR8 (0.35) | TLR8TLR7KDM4ETYMPALDH1A1 | |
| SCHEMBL11621518 | 0.69 | LMNA (0.46) | TLR8TLR7KDM4EALDH1A1 | |
| SCHEMBL11862558 | 0.69 | TYMP (0.38) | TLR8TLR7KDM4ETYMPALDH1A1 | |
| SCHEMBL12495762 | 0.69 | PDK2 (0.42) | TLR8TLR7KDM4ETYMPALDH1A1 | |
| SCHEMBL8243106 | 0.68 | HSP90AA1 (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611368-B1 | SUBSTITUTED AMINOPYRIMIDINES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PROD (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5336677-A | ANTAGONIST OF ANGIOTENSIN II | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-08-09 | — | — | US | disclosed |