Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.55 |
| ▸ | DRD3 | P35462 | 6/20 | 0.55 |
| ▸ | DRD4 | P21917 | 5/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907983 | 0.83 | DRD2 (0.66) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL8906340 | 0.80 | DRD2 (0.59) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL8906697 | 0.79 | DRD2 (0.72) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL8907838 | 0.77 | DRD2 (0.66) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL8907640 | 0.76 | DRD2 (0.67) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL9710672 | 0.73 | DRD2 (0.55) | DRD2DRD3DRD4 | |
| SCHEMBL8906622 | 0.72 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL8906889 | 0.72 | DRD2 (0.72) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL8906947 | 0.70 | DRD2 (0.70) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL8906529 | 0.70 | DRD2 (0.66) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556332-B1 | SUBSTITUTED TETRAHYDROPYRIDINES AND HYDROXYPIPERIDINES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER LAMBERT CO (US) | 1996-03-20 | — | — | EP | claimed |