Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP5 | Q96HI0 | 9/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 9/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 9/20 | 0.53 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024364 | 0.81 | SENP5 (0.55) | SENP5SENP2SENP1NMT1PTGS2 | |
| SCHEMBL9024708 | 0.81 | SENP5 (0.55) | SENP5SENP2SENP1NMT1PTGS2 | |
| SCHEMBL9025424 | 0.80 | PTGS2 (0.59) | SENP5SENP2SENP1NMT1PTGS2 | |
| Hydrochloric Acid SCHEMBL9304232 | 0.80 | SENP5 (0.60) | SENP5SENP2SENP1NMT1PTGS2 | |
| SCHEMBL9024182 | 0.79 | SENP5 (0.58) | SENP5SENP2SENP1NMT1PTGS2 | |
| Hydrochloric Acid SCHEMBL9305852 | 0.79 | SENP5 (0.48) | SENP5SENP2SENP1NMT1PTGS2 | |
| Hydrochloric Acid SCHEMBL9025254 | 0.79 | PTGS2 (0.58) | SENP5SENP2SENP1NMT1PTGS2 | |
| Hydrochloric Acid SCHEMBL9304862 | 0.78 | SENP5 (0.47) | SENP5SENP2SENP1NMT1LMNA | |
| Hydrochloric Acid SCHEMBL9024136 | 0.77 | SENP5 (0.55) | SENP5SENP2SENP1NMT1PTGS2 | |
| SCHEMBL11801079 | 0.77 | SENP5 (0.52) | SENP5SENP2SENP1NMT1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543584-B1 | Benzo(b)thiophene-2-carboxamides for the treatment of disorders of the central nervous system | LILLY INDUSTRIES LTD (GB) | 1996-05-22 | — | — | EP | disclosed |
| US-5338735-A | For treatment of central nervous system disorders | LILLY INDUSTRIES LIMITED (GB) | 1994-08-16 | — | — | US | disclosed |
| EP-0543584-A1 | Benzo(b)thiophene-2-carboxamides for the treatment of disorders of the central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1993-05-26 | — | — | EP | disclosed |