SCHEMBL9024334

SCHEMBL9024334

CCC1CNC(c2ccc(N)c(N)c2)=N1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP17A1 P05093 2/20 0.36
CYP19A1 P11511 2/20 0.36
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
CYP3A4 P08684 2/20 0.33
KCNH2 Q12809 2/20 0.33
ALDH1A1 P00352 3/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 2/20 0.31
POLB P06746 2/20 0.31
MAPT P10636 2/20 0.31
HSD17B10 Q99714 2/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9028811 0.72 DDAH1 (0.33) TSHRPOLBMAPTGAA
SCHEMBL7503977 0.70 NISCH (0.37) TDP1MEN1KMT2ACYP3A4ALDH1A1
Propane SCHEMBL21986397 0.66 TDP1 (0.78) TDP1MEN1KMT2ACYP17A1CYP19A1
Hydrochloric Acid SCHEMBL11549322 0.65 TDP1 (0.43) TDP1MEN1KMT2ACYP17A1CYP19A1
SCHEMBL9113381 0.65 TDP1 (0.43) TDP1MEN1KMT2ACYP17A1CYP19A1
SCHEMBL2491843 0.64 CYP3A4 (0.36) TDP1MEN1KMT2ACYP17A1CYP19A1
SCHEMBL1143063 0.64 NISCH (0.57)
SCHEMBL1627638 0.63 NISCH (0.37)
SCHEMBL9781549 0.63 GPR119 (0.55) MAPT
SCHEMBL9023407 0.62 TDP1 (0.41) TDP1MEN1KMT2ACYP17A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0720603-A1 BIS(AMIDINOBENZIMIDAZOLYL)ALKANES AS ANTIVIRAL AGENTS THE WELLCOME FOUNDATION LIMITED (GB) 1996-07-10 EP disclosed