Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27139926 | 0.85 | IDO1 (0.50) | IDO1TSHRCASP1HCAR3PRKCI | |
| SCHEMBL24443647 | 0.83 | TSHR (0.41) | IDO1TSHRCASP1GAAPDE10A | |
| SCHEMBL29509773 | 0.81 | IDO1 (0.53) | IDO1TSHRHCAR3GAAMAPT | |
| SCHEMBL15196187 | 0.79 | ALDH1A1 (0.45) | IDO1TSHRCASP1GAAPDE10A | |
| SCHEMBL25866513 | 0.79 | ALDH1A1 (0.46) | IDO1TSHRCASP1HCAR3GAA | |
| SCHEMBL23797765 | 0.78 | IDO1 (0.39) | IDO1CASP1HCAR3GAAMAPT | |
| SCHEMBL19848445 | 0.78 | IDO1 (0.39) | IDO1TSHRCASP1HCAR3PRKCI | |
| SCHEMBL17774803 | 0.76 | MITF (0.47) | IDO1HCAR3GAAMAPTPKM | |
| SCHEMBL11001118 | 0.76 | HTT (0.50) | GAAPKMALDH1A1NPC1RAB9A | |
| SCHEMBL11442397 | 0.76 | ALDH1A1 (0.45) | IDO1TSHRCASP1GAAPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591373-B1 | META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD | OREAL (FR) | 1996-05-22 | — | — | EP | claimed |