SCHEMBL902464

SCHEMBL902464

CC(Nc1ccnc2cc(Cl)ccc12)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.69
NR4A2 P43354 2/20 0.68
PKM P14618 1/20 0.56
TDP1 Q9NUW8 3/20 0.56
CHRM2 P08172 2/20 0.56
CHRM4 P08173 2/20 0.56
CHRM5 P08912 2/20 0.56
ADRA2A P08913 2/20 0.56
CHRM1 P11229 2/20 0.56
ADRA2B P18089 2/20 0.56
ADRA2C P18825 2/20 0.56
CHRM3 P20309 2/20 0.56
KCNH2 Q12809 2/20 0.56
TMEM97 Q5BJF2 2/20 0.56
SIGMAR1 Q99720 2/20 0.56
ACE2 Q9BYF1 2/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56
PRNP P04156 1/20 0.56
APP P05067 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30307409 0.83 GALR3 (0.59) TAAR1MAPTKMT2AMEN1ADRA1D
SCHEMBL9588226 0.81 NR4A2 (0.56) NR4A2PKMTDP1CHRM2CHRM4
SCHEMBL3398399 0.80 NR4A2 (0.76) TAAR1NR4A2TDP1CHRM2CHRM4
SCHEMBL8974915 0.78 GALR3 (0.70) MAPTLMNAKDM4E
SCHEMBL8975390 0.78 GALR3 (0.70) MAPTLMNAKDM4E
SCHEMBL5446408 0.78 NR4A2 (0.68) TAAR1NR4A2PKMTDP1CHRM2
SCHEMBL8975191 0.78 GALR3 (0.70) MAPTLMNAKDM4E
SCHEMBL7838139 0.78 NR4A2 (0.72) TAAR1NR4A2TDP1CHRM2CHRM4
SCHEMBL8540870 0.78 NR4A2 (0.72) TAAR1NR4A2TDP1CHRM2CHRM4
SCHEMBL9588156 0.77 NR4A2 (0.70) TAAR1NR4A2TDP1CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012041493-A1 AMINOQUINOLINIUM SALTS, METHODS OF THEIR PRODUCTION AND THEIR USE AS ACTIVE AGENTS FOR BIOTECHNOLOGICAL AND MEDICAL APPLICATIONS AGAINST BINARY TOXINS JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) 2012-04-05 WO disclosed