SCHEMBL30307409

SCHEMBL30307409

CC(Nc1ccnc2ccccc12)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GALR3 O60755 1/20 0.59
NR2F2 P24468 1/20 0.59
HTR1A P08908 2/20 0.51
ADRA1D P25100 2/20 0.51
ADRA1A P35348 2/20 0.51
ADRA1B P35368 2/20 0.51
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
TAAR1 Q96RJ0 1/20 0.47
CCNE2 O96020 3/20 0.47
CCNE1 P24864 3/20 0.47
CDK2 P24941 3/20 0.47
CDK4 P11802 2/20 0.47
CCND1 P24385 2/20 0.47
FERMT2 Q96AC1 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ERBB2 P04626 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28220542 0.91 GAA (0.53) GALR3NR2F2HTR1AADRA1DADRA1A
SCHEMBL8783600 0.91 ALDH1A1 (0.57) GALR3NR2F2MEN1MAPTHTT
SCHEMBL30307423 0.83 HTR1A (0.54) GALR3NR2F2HTR1AADRA1DADRA1A
SCHEMBL15912060 0.83 HTR1A (0.58) HTR1AADRA1DADRA1AADRA1BMAPT
SCHEMBL902464 0.83 TAAR1 (0.69) ADRA1DMEN1MAPTKMT2ATAAR1
SCHEMBL28501475 0.82 CRHBP (0.50) GALR3NR2F2HTR1AADRA1DADRA1A
SCHEMBL5948123 0.80 PLK1 (0.51)
SCHEMBL28860316 0.79 KRAS (0.50) HTR1AADRA1DADRA1AADRA1BFERMT2
SCHEMBL28220538 0.79 KRAS (0.50) HTR1AADRA1DADRA1AADRA1BFERMT2
SCHEMBL29516922 0.78 PTPN1 (0.51) HTR1AADRA1DADRA1AADRA1BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947684-A Method for preparing 4-aminoquinoline derivatives through palladium and copper concerted catalytic oxidation aromatization 贵州医科大学 2023-04-11 CN disclosed