Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.70 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.70 |
| ▸ | EGFR | P00533 | 8/20 | 0.63 |
| ▸ | KRAS | P01116 | 1/20 | 0.63 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 4/20 | 0.54 |
| ▸ | CNR2 | P34972 | 4/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975390 | 1.00 | GALR3 (0.70) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL8974915 | 1.00 | GALR3 (0.70) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL9921358 | 0.89 | GALR3 (0.70) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL13170943 | 0.89 | GALR3 (0.70) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL9921344 | 0.89 | GALR3 (0.70) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL17181108 | 0.83 | GALR3 (1.00) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL5312802 | 0.83 | GALR3 (1.00) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL4538841 | 0.81 | EGFR (0.70) | GALR3NR2F2EGFRKRASSOS1 | |
| SCHEMBL4538845 | 0.81 | EGFR (0.70) | GALR3NR2F2EGFRKRASSOS1 | |
| Hydrochloric Acid SCHEMBL7222518 | 0.80 | EGFR (0.68) | GALR3NR2F2EGFRKRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705253-A1 | ARALKYLAMINOQUINAZOLINES | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| EP-0705253-A1 | ARALKYLAMINOQUINAZOLINES | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000496-A1 | ARALKYLAMINOQUINAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-05 | — | — | WO | disclosed |
| WO-1995000496-A1 | ARALKYLAMINOQUINAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-05 | — | — | WO | disclosed |