Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CD69 | Q07108 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14694060 | 0.85 | KMT2A (0.49) | KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL14694190 | 0.81 | MGMT (0.36) | KMT2AHSD17B10ALOX15SMN1; SMN2POLB | |
| SCHEMBL9023776 | 0.81 | LMNA (0.42) | KMT2AHSD17B10KDM4E | |
| SCHEMBL14694191 | 0.79 | TSHR (0.54) | KMT2AMCL1L3MBTL1KDM4E | |
| SCHEMBL14694104 | 0.79 | GAA (0.45) | HPGDHSD17B10SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL14694059 | 0.79 | RAB9A (0.39) | KMT2ASMN1; SMN2POLBL3MBTL1KDM4E | |
| SCHEMBL14694114 | 0.79 | TSHR (0.62) | KMT2AHPGDSMN1; SMN2POLB | |
| SCHEMBL830740 | 0.78 | KMT2A (0.60) | KMT2ACD69HSD17B10ALOX15SMN1; SMN2 | |
| SCHEMBL2059355 | 0.78 | CSNK2A2 (0.49) | KMT2ACD69MCL1HPGDPTPRB | |
| SCHEMBL9025093 | 0.77 | POLB (0.53) | KMT2ACD69HPGDHSD17B10ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318415-B1 | OXAZOLOPYRIMIDINES AS EDG-1 RECEPTOR AGONISTS | SANOFI SA (FR) | 2013-02-20 | — | — | EP | disclosed |
| EP-0398179-B1 | Rhodanine derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5116855-A | Aldose reductase inhibitors; antidiabetic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0398179-A1 | Rhodanine derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |