Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901148 | 0.94 | ADORA2A (0.54) | P2RY12PRMT5WDR77ADORA3ADORA2A | |
| SCHEMBL439196 | 0.94 | ADORA2A (0.54) | P2RY12PRMT5WDR77ADORA3ADORA2A | |
| SCHEMBL7523809 | 0.91 | PRMT5 (0.45) | P2RY12PRMT5WDR77ADORA3BMPR1B | |
| SCHEMBL439195 | 0.91 | PRMT5 (0.45) | P2RY12PRMT5WDR77ADORA3BMPR1B | |
| SCHEMBL9294052 | 0.88 | ADORA2A (0.49) | P2RY12ADORA3ADORA2AADORA2B | |
| SCHEMBL2115367 | 0.86 | ADORA2A (0.55) | PRMT5WDR77ADORA3ADORA2AADORA2B | |
| SCHEMBL2115365 | 0.82 | PRMT5 (0.46) | PRMT5WDR77ADORA3BMPR1BADORA2A | |
| SCHEMBL313413 | 0.81 | LMNA (0.72) | ADORA3ADORA2AADORA2B | |
| SCHEMBL233209 | 0.81 | LMNA (0.72) | ADORA3ADORA2AADORA2B | |
| SCHEMBL21953578 | 0.81 | LMNA (0.72) | ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716856-A2 | Therapeutic uses of 2',5'-oligoadenylate derivatives | Temple University of the Commonwealth System of Higher Education (US) | 1996-06-19 | — | — | EP | disclosed |