Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439195 | 0.98 | PRMT5 (0.45) | PRMT5WDR77P2RY12ADORA2AADORA2B | |
| SCHEMBL2115365 | 0.91 | PRMT5 (0.46) | PRMT5WDR77ADORA2AADORA2BADORA3 | |
| SCHEMBL30901148 | 0.91 | ADORA2A (0.54) | PRMT5WDR77P2RY12ADORA2AADORA2B | |
| SCHEMBL439196 | 0.91 | ADORA2A (0.54) | PRMT5WDR77P2RY12ADORA2AADORA2B | |
| SCHEMBL9024698 | 0.91 | P2RY12 (0.49) | PRMT5WDR77P2RY12ADORA2AADORA2B | |
| SCHEMBL888000 | 0.85 | ADORA3 (0.43) | P2RY12ADORA2AADORA3 | |
| SCHEMBL2112012 | 0.85 | ADORA3 (0.43) | P2RY12ADORA3 | |
| SCHEMBL9294052 | 0.85 | ADORA2A (0.49) | P2RY12ADORA2AADORA2BADORA3 | |
| SCHEMBL2115367 | 0.84 | ADORA2A (0.55) | PRMT5WDR77ADORA2AADORA2BADORA3 | |
| SCHEMBL9155236 | 0.84 | TAS1R3 (0.36) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186306-A1 | Labeled nucleosides and method for their preparation | K.U. Leuven Research & Development (BE) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001085220-A1 | LABELED NUCLEOSIDES AND METHOD FOR THEIR PREPARATION | RNA-TEC N.V. (BE) | 2001-11-15 | — | — | WO | disclosed |