Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 18/20 | 0.63 |
| ▸ | NQO1 | P15559 | 10/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739746 | 0.92 | NQO2 (0.59) | NQO2NQO1MITF | |
| SCHEMBL9023520 | 0.90 | NQO2 (0.60) | NQO2NQO1 | |
| SCHEMBL9737559 | 0.90 | NQO2 (0.54) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL9739130 | 0.87 | NQO2 (0.46) | NQO2NQO1MITF | |
| SCHEMBL9023931 | 0.87 | NQO2 (0.47) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL9024106 | 0.86 | NQO2 (0.47) | NQO2NQO1MITF | |
| SCHEMBL9024920 | 0.86 | NQO2 (0.47) | NQO2NQO1MITF | |
| SCHEMBL9032596 | 0.85 | NQO2 (0.46) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL9024703 | 0.85 | NQO2 (0.48) | NQO2NQO1 | |
| SCHEMBL9738372 | 0.84 | NQO2 (0.46) | NQO2NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |