Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 12/20 | 0.46 |
| ▸ | NQO1 | P15559 | 8/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024575 | 0.87 | NQO2 (0.36) | NQO2NQO1HPGD | |
| SCHEMBL9024826 | 0.87 | NQO2 (0.63) | NQO2NQO1MITF | |
| SCHEMBL9738372 | 0.85 | NQO2 (0.46) | NQO2NQO1KAT2BKDM4EALDH1A1 | |
| SCHEMBL9024667 | 0.84 | NQO1 (0.39) | NQO2NQO1KDM4EALDH1A1 | |
| SCHEMBL9739746 | 0.81 | NQO2 (0.59) | NQO2NQO1MITF | |
| SCHEMBL9023717 | 0.80 | L3MBTL1 (0.43) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL9737559 | 0.78 | NQO2 (0.54) | NQO2NQO1MITF | |
| SCHEMBL9023520 | 0.77 | NQO2 (0.60) | NQO2NQO1 | |
| SCHEMBL9023847 | 0.76 | G6PD (0.39) | NQO2NQO1HPGD | |
| SCHEMBL9023722 | 0.76 | TOP2A (0.38) | NQO2NQO1HPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |