Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | DNM2 | P50570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739130 | 0.85 | NQO2 (0.46) | NQO2NQO1KAT2BALDH1A1KDM4E | |
| SCHEMBL2725699 | 0.84 | NQO1 (0.39) | NQO2NQO1ALDH1A1KDM4E | |
| SCHEMBL9024826 | 0.84 | NQO2 (0.63) | NQO2NQO1 | |
| SCHEMBL9739746 | 0.78 | NQO2 (0.59) | NQO2NQO1 | |
| SCHEMBL9024060 | 0.77 | KDM4E (0.51) | NQO2NQO1ALDH1A1KDM4EHPGD | |
| SCHEMBL9025023 | 0.77 | L3MBTL1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10PARP1 | |
| SCHEMBL9737559 | 0.75 | NQO2 (0.54) | NQO2NQO1 | |
| SCHEMBL9023931 | 0.75 | NQO2 (0.47) | NQO2NQO1 | |
| SCHEMBL9025088 | 0.74 | ALDH1A1 (0.40) | NQO2NQO1ALDH1A1KDM4EHPGD | |
| SCHEMBL9023686 | 0.74 | HTT (0.34) | NQO2NQO1KAT2BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |