Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | BRS3 | P32247 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671881 | 0.91 | LTB4R2 (0.57) | LTB4R2AGTR1BRS3 | |
| SCHEMBL8673632 | 0.86 | LTB4R2 (0.48) | LTB4R2AGTR1BRS3 | |
| SCHEMBL8670621 | 0.84 | LTB4R2 (0.51) | LTB4R2AGTR1BRS3 | |
| SCHEMBL633444 | 0.83 | MME (0.48) | LTB4R2AGTR1 | |
| SCHEMBL9205175 | 0.83 | LTB4R2 (0.48) | LTB4R2 | |
| SCHEMBL8979746 | 0.81 | LTB4R2 (0.55) | LTB4R2AGTR1BRS3 | |
| SCHEMBL1371403 | 0.80 | MME (0.48) | AGTR1 | |
| SCHEMBL8979799 | 0.79 | LTB4R2 (0.53) | LTB4R2AGTR1BRS3 | |
| SCHEMBL9204918 | 0.79 | LTB4R2 (0.40) | LTB4R2 | |
| SCHEMBL9137311 | 0.77 | AGTR1 (0.40) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500409-B1 | 4-Pyrimidinone derivatives, their preparation and their application in therapy | SYNTHELABO (FR) | 1996-03-20 | — | — | EP | disclosed |
| EP-0500409-A1 | 4-Pyrimidinone derivatives, their preparation and their application in therapy | SYNTHELABO (FR) | 1992-08-26 | — | — | EP | disclosed |