Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 18/20 | 0.45 |
| ▸ | NQO1 | P15559 | 11/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023829 | 0.94 | NQO2 (0.43) | NQO2NQO1MITFCCR6PAX8 | |
| SCHEMBL9023946 | 0.91 | NQO2 (0.42) | NQO2NQO1MITFCCR6PAX8 | |
| SCHEMBL9023509 | 0.84 | NQO2 (0.33) | NQO2NQO1MITFCCR6PAX8 | |
| SCHEMBL9024234 | 0.82 | BRD4 (0.44) | NQO2NQO1 | |
| SCHEMBL9023520 | 0.80 | NQO2 (0.60) | NQO2NQO1 | |
| SCHEMBL9739746 | 0.79 | NQO2 (0.59) | NQO2NQO1MITF | |
| SCHEMBL9737559 | 0.76 | NQO2 (0.54) | NQO2NQO1MITF | |
| SCHEMBL9024920 | 0.76 | NQO2 (0.47) | NQO2NQO1MITF | |
| SCHEMBL9024106 | 0.76 | NQO2 (0.47) | NQO2NQO1MITF | |
| SCHEMBL9024703 | 0.75 | NQO2 (0.48) | NQO2NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |