Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | NQO2 | P16083 | 7/20 | 0.43 |
| ▸ | NQO1 | P15559 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024051 | 0.83 | CD274 (0.41) | BRD4HTTLMNASMN1; SMN2 | |
| SCHEMBL9024984 | 0.82 | NQO2 (0.45) | NQO2NQO1 | |
| SCHEMBL9024703 | 0.78 | NQO2 (0.48) | NQO2NQO1 | |
| SCHEMBL9023796 | 0.68 | NQO2 (0.47) | NQO2NQO1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL3067744 | 0.68 | HTT (0.67) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL4373055 | 0.68 | HTT (0.67) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL9023722 | 0.68 | TOP2A (0.38) | NQO2NQO1 | |
| SCHEMBL9023814 | 0.67 | NQO2 (0.36) | NQO2NQO1HTT | |
| SCHEMBL1299850 | 0.67 | HTT (0.72) | HTTTGM2KEAP1NFE2L2DPP8 | |
| SCHEMBL7877730 | 0.67 | HTT (0.72) | HTTTGM2KEAP1NFE2L2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |