Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 9/20 | 0.33 |
| ▸ | NQO1 | P15559 | 5/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024639 | 0.87 | NQO2 (0.42) | NQO2NQO1PAX8MITF | |
| SCHEMBL9023862 | 0.85 | NQO2 (0.36) | NQO2NQO1 | |
| SCHEMBL9024984 | 0.84 | NQO2 (0.45) | NQO2NQO1CCR6PAX8MITF | |
| SCHEMBL9024021 | 0.83 | NQO1 (0.34) | NQO2NQO1 | |
| SCHEMBL9023942 | 0.82 | NQO1 (0.35) | NQO2NQO1 | |
| SCHEMBL9023350 | 0.82 | TOP2A (0.38) | NQO2NQO1PAX8 | |
| SCHEMBL9023829 | 0.82 | NQO2 (0.43) | NQO2NQO1CCR6PAX8MITF | |
| SCHEMBL9025443 | 0.81 | NQO2 (0.37) | NQO2NQO1 | |
| SCHEMBL9023931 | 0.79 | NQO2 (0.47) | NQO2NQO1MITF | |
| SCHEMBL9023796 | 0.77 | NQO2 (0.47) | NQO2NQO1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |