Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673174 | 1.00 | KCNN4 (0.50) | KCNN4KIF11CYP2D6CYP1A2MAPK1 | |
| SCHEMBL2160833 | 0.77 | KCNN4 (0.50) | KCNN4KIF11CYP2D6CYP1A2MAPK1 | |
| SCHEMBL4495324 | 0.77 | KCNN4 (0.50) | KCNN4KIF11CYP2D6CYP1A2CHRM2 | |
| SCHEMBL10675289 | 0.77 | KCNN4 (0.50) | KCNN4KIF11CYP2D6CYP1A2MAPK1 | |
| SCHEMBL2771122 | 0.75 | CYP1A2 (0.40) | KCNN4KIF11CYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL19381442 | 0.74 | KCNN4 (0.46) | KCNN4KIF11CYP2D6CYP1A2TDP1 | |
| SCHEMBL16609226 | 0.74 | KCNN4 (0.52) | KCNN4KIF11TDP1CACNA1FCHRM2 | |
| SCHEMBL6566499 | 0.74 | KCNN4 (0.52) | KCNN4KIF11TDP1CACNA1FCHRM2 | |
| SCHEMBL7556522 | 0.74 | KCNN4 (0.46) | KCNN4KIF11CYP2D6CYP1A2MAPK1 | |
| SCHEMBL2552806 | 0.72 | KCNN4 (0.45) | KCNN4KIF11CYP2D6CYP1A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066106-A1 | STABLE PANTETHEINE DERIVATIVES FOR THE TREATMENT OF PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION (PKAN) AND METHODS FOR THE SYNTHESIS OF SUCH COMPOUNDS | Acies Bio d.o.o. (SI) | 2016-09-14 | — | — | EP | claimed |
| WO-2015063177-A1 | STABLE PANTETHEINE DERIVATIVES FOR THE TREATMENT OF PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION (PKAN) AND METHODS FOR THE SYNTHESIS OF SUCH COMPOUNDS | ACIES BIO D.O.O. (SI) | 2015-05-07 | — | — | WO | claimed |
| CN-120059164-A | PH responsive polypeptide mimic and preparation method and application thereof | 华东理工大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-113185740-B | Method for improving antibacterial activity and biocompatibility of substrate surface | 华东理工大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-116554461-A | Use of polymers to promote endothelialization of interventional/implant materials | 华东理工大学 | 2023-08-08 | — | — | CN | disclosed |
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| EP-0002564-B1 | DERIVATIVES OF 7-OXO-1-AZABICYCLO(3.2.0)-HEPT-2-ENE-2-CARBOXYLIC ACID, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1984-06-20 | — | — | EP | disclosed |
| US-4347181-A | Intermediates for producing bicyclic β-lactam-antibiotics | BEECHAM GROUP LIMITED (GB) | 1982-08-31 | — | — | US | disclosed |
| US-4289696-A | BETA-LACTAMASE INHIBITORY AGENTS WHICH ENHANCE ACTIVITY OF A PENICICILLIN OR CEPHALOSPORIN | BEECHAM GROUP LIMITED (GB) | 1981-09-15 | — | — | US | disclosed |
| US-4223038-A | THIENAMYCINS | BEECHAM GROUP LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| EP-0002564-A1 | Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1979-06-27 | — | — | EP | disclosed |