Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695255 | 0.79 | CA1 (0.36) | KCNN4TDP1 | |
| SCHEMBL10675289 | 0.77 | KCNN4 (0.50) | KCNN4KIF11CYP1A2CYP2D6TAAR1 | |
| SCHEMBL9025613 | 0.77 | KCNN4 (0.50) | KCNN4KIF11CYP1A2CYP2D6TAAR1 | |
| SCHEMBL4495324 | 0.77 | KCNN4 (0.50) | KCNN4KIF11CYP1A2CYP2D6SLC6A4 | |
| SCHEMBL16673174 | 0.77 | KCNN4 (0.50) | KCNN4KIF11CYP1A2CYP2D6TAAR1 | |
| SCHEMBL19381442 | 0.74 | KCNN4 (0.46) | KCNN4KIF11CYP1A2CYP2D6SLC6A4 | |
| SCHEMBL16609226 | 0.74 | KCNN4 (0.52) | KCNN4KIF11TAAR1SLC6A3SIGMAR1 | |
| SCHEMBL7556522 | 0.74 | KCNN4 (0.46) | KCNN4KIF11CYP1A2CYP2D6SLC6A4 | |
| SCHEMBL6566499 | 0.74 | KCNN4 (0.52) | KCNN4KIF11TAAR1SLC6A3SIGMAR1 | |
| SCHEMBL2552806 | 0.72 | KCNN4 (0.45) | KCNN4KIF11CYP1A2CYP2D6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099808-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | NIRVANA'S TREE HOUSE B.V. (NL) | 2015-04-09 | — | — | US | disclosed |
| US-20110182813-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | NIRVANA'S TREE HOUSE B.V. (NL) | 2011-07-28 | — | — | US | disclosed |
| EP-2195366-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | Nirvana's Tree House B.v. (NL) | 2010-06-16 | — | — | EP | disclosed |
| EP-2042538-A1 | Amphiphilic copolymers and compositions containing such polymers | Nirvana's Tree House (NL) | 2009-04-01 | — | — | EP | disclosed |
| WO-2009037313-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | NIRVANA'S TREE HOUSE B.V. (NL) | 2009-03-26 | — | — | WO | disclosed |
| US-7005123-B1 | Functional poly-α-amino-acid derivatives useful for the modification of biologically active materials and their application | UNIVERSITEIT GENT (BE) | 2006-02-28 | — | — | US | disclosed |
| EP-1189971-B1 | FUNCTIONAL POLY-ALPHA-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION | UNIV GENT (BE) | 2005-03-09 | — | — | EP | disclosed |
| EP-1189971-A2 | FUNCTIONAL POLY-ALPHA-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION | UNIVERSITEIT GENT (BE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000078791-A2 | FUNCTIONAL POLY-α-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION | UNIVERSITEIT GENT (BE) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182813-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | GLUL, ASNS, ARGLU1 | KCNN4 4093/4885KIF11 1618/4885CYP1A2 4855/4885 |
| US-20150099808-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | GLUL, ASNS, ARGLU1 | KCNN4 4093/4885KIF11 1618/4885CYP1A2 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.