Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027493 | 1.00 | TACR3 (0.43) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL9026296 | 0.87 | TACR3 (0.42) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL9026652 | 0.81 | TACR3 (0.47) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL9026879 | 0.76 | KMT2A (0.57) | TACR2L3MBTL1MEN1KMT2A | |
| SCHEMBL9026715 | 0.76 | KMT2A (0.57) | TACR2L3MBTL1MEN1KMT2A | |
| SCHEMBL16399234 | 0.73 | TACR3 (0.53) | TACR3KDM1AMAOARCOR1HTR2C | |
| SCHEMBL16398195 | 0.72 | L3MBTL1 (0.49) | TACR3KDM1AMAOARCOR1HTR2C | |
| SCHEMBL9116988 | 0.71 | TACR3 (0.49) | TACR3KDM1AMAOARCOR1L3MBTL1 | |
| SCHEMBL12359746 | 0.71 | L3MBTL1 (0.51) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL2253248 | 0.71 | TACR3 (0.51) | TACR3KDM1AMAOARCOR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |