Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | CAPN2 | P17655 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026296 | 0.87 | TACR3 (0.42) | TACR3TACR1HDAC3HDAC1HDAC2 | |
| SCHEMBL9025919 | 0.81 | TACR3 (0.43) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL9027493 | 0.81 | TACR3 (0.43) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL9026791 | 0.80 | KMT2A (0.40) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL9027529 | 0.80 | KMT2A (0.40) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL9482166 | 0.77 | TACR3 (0.44) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL10467137 | 0.76 | HDAC3 (0.48) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL16399234 | 0.76 | TACR3 (0.53) | TACR3KDM1AMAOARCOR1MEN1 | |
| SCHEMBL9026662 | 0.75 | TACR3 (0.41) | TACR3TACR1KDM1AMAOARCOR1 | |
| SCHEMBL16398195 | 0.74 | L3MBTL1 (0.49) | TACR3KDM1AMAOARCOR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |