Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506375 | 0.91 | PTGS2 (0.51) | PTGS2PTGS1NR4A2 | |
| SCHEMBL7506922 | 0.89 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL7504045 | 0.87 | PTGS2 (0.52) | PTGS2PTGS1NR4A2 | |
| SCHEMBL7501033 | 0.86 | PTGS2 (0.51) | PTGS2PTGS1NR4A2 | |
| SCHEMBL7500555 | 0.86 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL9025618 | 0.86 | PTGS2 (0.48) | PTGS2PTGS1NR4A2 | |
| SCHEMBL7506543 | 0.85 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL7511037 | 0.85 | RXRA (0.53) | PTGS2PTGS1NR4A2 | |
| SCHEMBL7505741 | 0.85 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL9026802 | 0.85 | PTGS2 (0.57) | PTGS2PTGS1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |