Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026305 | 0.98 | PDE3B (0.35) | PDE3BPDE3AP2RY12CYP2C9KMT2A | |
| SCHEMBL8502645 | 0.92 | ALDH1A1 (0.39) | CYP2C9KMT2AALDH1A1WDR5MAPT | |
| SCHEMBL8548759 | 0.92 | KMT2A (0.40) | CYP2C9KMT2AALDH1A1WDR5MAPT | |
| SCHEMBL23988379 | 0.91 | ATP1A1 (0.35) | CYP2C9KMT2AALDH1A1WDR5MAPT | |
| SCHEMBL8550337 | 0.90 | CYP2C9 (0.34) | PDE3BPDE3AP2RY12CYP2C9KMT2A | |
| SCHEMBL8548748 | 0.90 | KMT2A (0.40) | CYP2C9KMT2AALDH1A1WDR5MAPT | |
| SCHEMBL23988383 | 0.88 | KMT2A (0.46) | CYP2C9KMT2AALDH1A1WDR5MAPT | |
| SCHEMBL8550333 | 0.88 | CYP2C9 (0.34) | PDE3BPDE3AP2RY12CYP2C9KMT2A | |
| SCHEMBL8504605 | 0.88 | TLR8 (0.38) | PDE3BPDE3AP2RY12CYP2C9KMT2A | |
| SCHEMBL23988394 | 0.88 | KMT2A (0.46) | CYP2C9KMT2AALDH1A1WDR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295603-B1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | EISAI CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| EP-0295603-A1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | Eisai Co., Ltd. (JP) | 1988-12-21 | — | — | EP | disclosed |