Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PAICS | P22234 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025816 | 0.92 | KDM4E (0.35) | KDM4EL3MBTL1PAICS | |
| SCHEMBL9025961 | 0.90 | KDM4E (0.34) | KDM4EL3MBTL1 | |
| SCHEMBL9025304 | 0.81 | KDM4E (0.37) | KDM4EL3MBTL1 | |
| SCHEMBL9025502 | 0.79 | PDE7A (0.37) | KDM4EL3MBTL1PAICS | |
| SCHEMBL9025657 | 0.79 | MAPK14 (0.37) | KDM4EL3MBTL1PAICS | |
| Water SCHEMBL9025694 | 0.75 | MEN1 (0.41) | KDM4E | |
| Water SCHEMBL9025692 | 0.75 | MEN1 (0.41) | KDM4E | |
| SCHEMBL9025609 | 0.74 | TLR8 (0.44) | — | |
| SCHEMBL9026614 | 0.71 | SIGMAR1 (0.43) | — | |
| Water SCHEMBL9218000 | 0.71 | HRH3 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | claimed |