Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amitraz SCHEMBL3957192 | 0.91 | CYP3A4 (1.00) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL13346111 | 0.91 | CYP3A4 (1.00) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL1765794 | 0.91 | CYP3A4 (1.00) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL2471817 | 0.91 | CYP3A4 (1.00) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL19312984 | 0.91 | CYP3A4 (1.00) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL29370387 | 0.91 | CYP3A4 (1.00) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL37309 | 0.91 | CYP3A4 (1.00) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL2471853 | 0.91 | CYP3A4 (1.00) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL890417 | 0.90 | CYP3A4 (0.96) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL27987034 | 0.88 | CYP3A4 (0.80) | CYP3A4ADRA2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210378263-A1 | BIOREMEDIATION OF XENOBIOTICS IN THE HONEY BEE HIVE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-12-09 | — | — | US | disclosed |
| WO-2016075673-A1 | GENETIC MARKERS FOR DETERMINING ECTOPARASITE SUSCEPTIBILITY TO ACARICIDES | UNIVERSITY OF PRETORIA (ZA) | 2016-05-19 | — | — | WO | disclosed |
| EP-0500755-B1 | PYRIDINE DERIVATIVES, PROCESS FOR MAKING THEM, AGENTS CONTAINING THEM AND THEIR USE AS FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-05-15 | — | — | EP | disclosed |
| EP-0563208-A1 | SULPHONYL FORMAMIDOXIMES, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE AGAINST PLANT PESTS | Hoechst Schering AgrEvo GmbH (DE) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992022526-A1 | SULPHONYL FORMAMIDRAZONES, METHODS OF PREPARING THEM, AGENTS CONTAINING THEM, AND THEIR USE AGAINST PLANT PESTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | WO | disclosed |
| EP-0500755-A1 | PYRIDINE DERIVATIVES, PROCESS FOR MAKING THEM, AGENTS CONTAINING THEM AND THEIR USE AS FUNGICIDES. | HOECHST AG (DE) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992011237-A1 | SULPHONYL FORMAMIDOXIMES, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE AGAINST PLANT PESTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-09 | — | — | WO | disclosed |
| EP-0481405-A1 | Pyrimidin derivatives, process for their préparation, agents containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0469357-A1 | 1-[pyri(mi)dyl-(2)]-5-hydroxypyrazole microbicides | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |
| EP-0249015-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM, AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-27 | — | — | EP | disclosed |
| EP-0317881-A2 | Pyridyl- and pyrazinyl compounds, process for their preparation, composition containing them and their use as fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-31 | — | — | EP | disclosed |
| EP-0249015-A1 | Silane derivatives, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-16 | — | — | EP | disclosed |
| US-4607050-A | Method of controlling insects and parasites with an aqueous localized pour-on formulation | WELLCOME AUSTRALIA LIMITED (AU) | 1986-08-19 | — | — | US | disclosed |