Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9026528 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL9027065 | 0.81 | DRD2 (0.60) | — | |
| SCHEMBL9027717 | 0.79 | DRD2 (0.69) | — | |
| Hydrochloric Acid SCHEMBL9026741 | 0.78 | DRD2 (0.68) | — | |
| SCHEMBL9027775 | 0.78 | — | — | |
| Oxalic Acid SCHEMBL8828479 | 0.76 | DRD2 (0.65) | — | |
| Hydrochloric Acid SCHEMBL9026124 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL8828515 | 0.74 | — | — | |
| SCHEMBL8828567 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL8828660 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711757-A1 | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists | F. Hoffmann-La Roche AG (CH) | 1996-05-15 | — | — | EP | disclosed |