Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.35 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550415 | 0.98 | CYP2C9 (0.36) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8502925 | 0.91 | KMT2A (0.37) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8548632 | 0.91 | KMT2A (0.38) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10335436 | 0.91 | CYP2C9 (0.39) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8548629 | 0.90 | KMT2A (0.38) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8500412 | 0.89 | CYP2C9 (0.38) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8503950 | 0.88 | CYP2C9 (0.38) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9026380 | 0.88 | CYP2C9 (0.35) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8550337 | 0.88 | CYP2C9 (0.34) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8503958 | 0.88 | KMT2A (0.44) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295603-B1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | EISAI CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |