Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | WDR5 | P61964 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | FASN | P49327 | 2/20 | 0.38 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548632 | 0.98 | KMT2A (0.38) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL8502925 | 0.96 | KMT2A (0.37) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL8503958 | 0.95 | KMT2A (0.44) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL8550415 | 0.91 | CYP2C9 (0.36) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL8500412 | 0.90 | CYP2C9 (0.38) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL5662759 | 0.90 | ATP4A (0.42) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL9026751 | 0.90 | CYP2C9 (0.36) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL6872754 | 0.89 | CYP2C9 (0.48) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL10335436 | 0.89 | CYP2C9 (0.39) | KMT2AALDH1A1CYP2C9WDR5HPGD | |
| SCHEMBL9026374 | 0.88 | CYP2C9 (0.35) | KMT2AALDH1A1CYP2C9WDR5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0295603-B1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | EISAI CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| EP-0295603-A1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | Eisai Co., Ltd. (JP) | 1988-12-21 | — | — | EP | disclosed |