Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATP1A1 | P05023 | 5/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 5/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 5/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 5/20 | 0.37 |
| ▸ | ATP4A | P20648 | 5/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 5/20 | 0.37 |
| ▸ | ATP4B | P51164 | 5/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 5/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 5/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 5/20 | 0.37 |
| ▸ | WDR5 | P61964 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548632 | 0.90 | KMT2A (0.38) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8503958 | 0.90 | KMT2A (0.44) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8548629 | 0.90 | KMT2A (0.38) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6872754 | 0.90 | CYP2C9 (0.48) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10335436 | 0.90 | CYP2C9 (0.39) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5662759 | 0.89 | ATP4A (0.42) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8550415 | 0.89 | CYP2C9 (0.36) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8502925 | 0.89 | KMT2A (0.37) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9026751 | 0.89 | CYP2C9 (0.36) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8133803 | 0.86 | ATP4A (0.41) | CYP2C9NPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998445-A | PEPTIC ULCERS | EISAI CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0654471-B1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and process for preparing the same | EISAI CO LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0268956-B2 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | EISAI CO LTD (JP) | 1998-04-15 | — | — | EP | disclosed |
| EP-0786461-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1997-07-30 | — | — | EP | disclosed |
| EP-0654471-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and process for preparing the same | Eisai Co., Ltd. (JP) | 1995-05-24 | — | — | EP | disclosed |
| EP-0475456-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-5045552-A | Pyridine derivatives having anti-ulcerative activity | EISAI CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0268956-A2 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1988-06-01 | — | — | EP | disclosed |