Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026699 | 0.85 | RAB9A (0.36) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL9026095 | 0.83 | HPGD (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9026454 | 0.83 | PTGS2 (0.39) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9026794 | 0.82 | CCNC (0.33) | KDM4EALDH1A1HPGDGAARAB9A | |
| SCHEMBL9026419 | 0.81 | HPGD (0.48) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9025850 | 0.81 | RAB9A (0.37) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9026398 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9026343 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9026261 | 0.79 | TSHR (0.39) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9025661 | 0.79 | TSHR (0.46) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |