Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026838 | 1.00 | PIK3CD (0.35) | PIK3CDGPR119POLBSIGMAR1SNCA | |
| SCHEMBL9027794 | 0.87 | GPR119 (0.33) | GPR119SIGMAR1CYP19A1 | |
| SCHEMBL9027799 | 0.87 | GPR119 (0.33) | GPR119SIGMAR1CYP19A1 | |
| SCHEMBL8832922 | 0.83 | SNCA (0.38) | PIK3CDGPR119POLBSIGMAR1SNCA | |
| SCHEMBL9221010 | 0.83 | SNCA (0.38) | PIK3CDGPR119POLBSIGMAR1SNCA | |
| SCHEMBL9025782 | 0.82 | ECE1 (0.37) | GPR119CYP19A1KDM4EALDH1A1NPSR1 | |
| SCHEMBL9025780 | 0.82 | ECE1 (0.37) | GPR119CYP19A1KDM4EALDH1A1NPSR1 | |
| SCHEMBL9222414 | 0.81 | CHRNA7 (0.41) | PIK3CDPOLBSIGMAR1CYP19A1ALDH1A1 | |
| SCHEMBL9222410 | 0.81 | CHRNA7 (0.41) | PIK3CDPOLBSIGMAR1CYP19A1ALDH1A1 | |
| SCHEMBL9216990 | 0.79 | CYP19A1 (0.33) | POLBSIGMAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |