Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027794 | 1.00 | GPR119 (0.33) | GPR119MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL9026838 | 0.87 | PIK3CD (0.35) | GPR119CYP19A1SIGMAR1 | |
| SCHEMBL9026845 | 0.87 | PIK3CD (0.35) | GPR119CYP19A1SIGMAR1 | |
| SCHEMBL8833776 | 0.82 | SIGMAR1 (0.33) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL9220068 | 0.82 | SIGMAR1 (0.33) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL9212026 | 0.81 | MMP2 (0.34) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL8832958 | 0.81 | MMP2 (0.34) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL8834267 | 0.80 | DRD2 (0.37) | MMP2CYP19A1 | |
| SCHEMBL9215805 | 0.80 | DRD2 (0.37) | MMP2CYP19A1 | |
| SCHEMBL9027764 | 0.80 | MMP2 (0.34) | MMP2ANPEPCYP19A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |