Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026928 | 1.00 | GNRHR (0.33) | GNRHRACHEMAPTHRH3THRB | |
| SCHEMBL9027714 | 0.80 | SIGMAR1 (0.43) | MAPTPOLBLMNA | |
| SCHEMBL3400412 | 0.80 | SIGMAR1 (0.43) | MAPTPOLBLMNA | |
| SCHEMBL8832661 | 0.80 | SIGMAR1 (0.43) | MAPTPOLBLMNA | |
| SCHEMBL9026664 | 0.78 | DRD2 (0.34) | MAPTTHRBCHRM2CHRM4CHRM5 | |
| SCHEMBL1440293 | 0.78 | SIGMAR1 (0.42) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1440297 | 0.78 | SIGMAR1 (0.42) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL31309170 | 0.78 | SIGMAR1 (0.42) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL30204127 | 0.78 | MAPT (0.39) | MAPTTHRBCHRM2CHRM4CHRM5 | |
| SCHEMBL18387532 | 0.78 | SIGMAR1 (0.42) | MAPTCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |