Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953786 | 0.82 | CA2 (0.46) | CA2CA1ALDH1A1CTBP2CA9 | |
| SCHEMBL953785 | 0.82 | CA2 (0.46) | CA2CA1ALDH1A1CTBP2CA9 | |
| SCHEMBL11110696 | 0.80 | CTBP2 (0.59) | CA2CA1ALDH1A1CTBP2CA9 | |
| SCHEMBL11110698 | 0.80 | CTBP2 (0.59) | CA2CA1ALDH1A1CTBP2CA9 | |
| SCHEMBL9027512 | 0.79 | MAOB (0.38) | CA2CA1CA9PPARGPPARA | |
| SCHEMBL23780246 | 0.79 | CA2 (0.46) | CA2CA1ALDH1A1CTBP2CA9 | |
| SCHEMBL28759575 | 0.79 | MAPT (0.46) | ALDH1A1PPARGPPARALMNAMAPT | |
| SCHEMBL20446972 | 0.79 | CA2 (0.46) | CA2CA1ALDH1A1CTBP2CA9 | |
| SCHEMBL19053351 | 0.79 | CA2 (0.46) | CA2CA1ALDH1A1CTBP2CA9 | |
| Hydrochloric Acid SCHEMBL7118313 | 0.76 | PPARG (0.44) | CA2CA1ALDH1A1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |